Blar i forfatter "Langhammer, Arnulf"

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    • Adiposity and asthma in adults: a bidirectional Mendelian randomization analysis of the HUNT Study 

      Sun, Yi-Qian; Brumpton, Ben Michael; Langhammer, Arnulf; Chen, Yue; Kvaløy, Kirsti; Mai, Xiao-Mei (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-14)
      <i>Background</i> - We aimed to investigate the potential causal associations of adiposity with asthma overall, asthma by atopic status or by levels of symptom control in a large adult population and stratified by sex. We also investigated the potential for reverse causation between asthma and risk of adiposity.<p> <p><i>Methods</i> - We performed a bidirectional one-sample Mendelian randomisation ...

    • Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT Study 

      Sun, Yi-Qian; Richmond, Rebecca C.; Suderman, Matthew; Min, Josine L; Battram, Thomas; Flatberg, Arnar; Beisvag, Vidar; Nøst, Therese Haugdahl; Guida, Florence; Jiang, Lin; Wahl, Sissel Gyrid Freim; Langhammer, Arnulf; Skorpen, Frank; Walker, Rosie M; Bretherick, Andrew D; Zeng, Yanni; Chen, Yue; Johansson, Mattias; Sandanger, Torkjel M; Relton, Caroline L; Mai, Xiao-Mei (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-17)
      <i>Background</i> - It is unclear if smoking-related DNA methylation represents a causal pathway between smoking and risk of lung cancer. We sought to identify novel smoking-related DNA methylation sites in blood, with repeated measurements, and to appraise the putative role of DNA methylation in the pathway between smoking and lung cancer development.<br><br> <i>Methods</i> - We derived a nested ...

    • The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium 

      Guida, Florence; Tan, VY; Smith-Byrne, K; Alcala, Karine; Langenberg, C; Butterworth, AS; Surendran, P; Achaintre, David; Adamski, P; Bergmann, MM; Bull, CJ; Dahm, CC; Gicquiau, Audrey; Giles, GG; Gunter, MJ; Haller, T; Langhammer, Arnulf; Larose, TL; Ljungberd, B; Metspalu, A; Milne, RL; Muller, DC; Nøst, Therese Haugdahl; Sørgjerd, Elin Pettersen; Prehn, C; Riboli, E; Rinaldi, S; Rothwell, JA; Scalbert, A.; Severi, G; Sieri, S; Vermeulen, R; Vincent, EE; Waldenberger, M; Timpson, NJ; Johansson, M; Corbin, Laura J.; Stewart, Isobel D.; Amiano, Pilar; Schmidt, Julie A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-20)

    • Cohort Profile Update: The Young-HUNT Study, Norway 

      Rangul, Vegar; Holmen, Turid Lingaas; Langhammer, Arnulf; Ingul, Jo Magne; Pape, Kristine; Fenstad, Jørn Søberg; Kvaløy, Kirsti (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-01)

    • Global Lung Function Initiative 2012 reference equations for spirometry in the Norwegian Population 

      Langhammer, Arnulf; Johannessen, Ane; Holmen, Turid Lingaas; Melbye, Hasse; Stanojevic, Sanja; Lund, May Brit; Melsom, Morten Nissen; Bakke, Per S.; Quanjer, Philip (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-06)
      <b>Background:</b> We studied the fit of the Global Lung Function Initiative all-age reference values to Norwegians, compared them with currently used references (European Community for Steel and Coal (ECSC) and Zapletal) and estimated the prevalence of obstructive lung disease.<br> <b>Methods:</b> Spirometry data collected in 30,239 subjects (51.7% females) aged 12-90 years in three population-based ...

    • Is the Disease Burden from COPD in Norway Falling off? A Study of Time Trends in Three Different Data Sources 

      Melbye, Hasse; Helgeland, Jon; Karlstad, Øystein; Ariansen, Inger; Langhammer, Arnulf; Wisløff, Torbjørn; Nafstad, Per; Nystad, Wenche (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-12)
      <i>Background</i>: Less smoking should lead to fewer COPD cases. We aimed at estimating time trends in the prevalence and burden of COPD in Norway from 2001 to 2017.<p><p> <i>Methods</i>: We used pre-bronchodilator spirometry and other health data from persons aged 40– 84 years in three surveys of the Tromsø Study, 2001– 2002, 2007– 2008 and 2015– 2016. We applied spirometry lower limits of normal ...

    • Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools 

      Feng, Xiaoshuang; Wu, Wendy Yi-Ying; Onwuka, Justina Ucheojor; Haider, Zahra; Alcala, Karine; Smith-Byrne, Karl; Zahed, Hana; Guida, Florence; Wang, Renwei; Bassett, Julie K.; Stevens, Victoria; Wang, Ying; Weinstein, Stephanie; Freedman, Neal D.; Chen, Chu; Tinker, Lesley; Nøst, Therese Haugdahl; Koh, Woon-Puay; Muller, David; Colorado-Yohar, Sandra M.; Tumino, Rosario; Hung, Rayjean J.; Amos, Christopher I.; Lin, Xihong; Zhang, Xuehong; Arslan, Alan A.; Sánchez, Maria-Jose; Sørgjerd, Elin Pettersen; Severi, Gianluca; Hveem, Kristian; Brennan, Paul; Langhammer, Arnulf; Milne, Roger L.; Yuan, Jian-Min; Melin, Beatrice; Johansson, Mikael; Robbins, Hilary A.; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-01)
      Background: We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available autoantibody biomarker test.<p><p>Methods: We designed a case-control study nested in 6 prospective cohorts, including 624 lung cancer participants who donated blood samples at most 3 ...

    • National health registries – a ‘goldmine’ for studying non-communicable disease occurrence in Norway – the NCDNOR project 

      Nystad, Wenche; Hjellvik, Vidar; Larsen, Inger Kristin; Robsahm, Trude Eid; Sund, Erik Reidar; Krokstad, Steinar; Hopstock, Laila Arnesdatter; Grimsgaard, Anne Sameline; Langhammer, Arnulf; Bramness, Jørgen Gustav; Wisløff, Torbjørn; Lergenmuller, Simon; Dalene, Knut Eirik; Meyer, Haakon Eduard; Holvik, Kristin; Helgeland, Jon; Karlstad, Øystein; Ariansen, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-10)
      To estimate occurrence of non-communicable diseases (NCDs) over the life-course in the Norwegian population, national health registries are a vital source of information since they fully represent the entire non-institutionalised population. However, as they are mainly established for administrative purposes, more knowledge about how NCDs are recorded in the registries is needed. To establish this, ...

    • Prediagnosis Leisure-Time Physical Activity and Lung Cancer Survival: A Pooled Analysis of 11 Cohorts 

      Yang, Jae Jeong; Yu, Danxia; White, Emily; Lee, Dong Hoon; Blot, William; Robien, Kim; Park, Yikyung; Takata, Yumie; Gao, Yu-Tang; Smith-Byrne, Karl; Monninkhof, Evelyn M; Kaaks, Rudolf; Langhammer, Arnulf; Borch, Kristin Benjaminsen; Al-Shaar, Laila; Lan, Qing; Sørgjerd, Elin Pettersen; Zhang, Xuehong; Zhu, Clair; Chirlaque, María Dolores; Severi, Gianluca; Overvad, Kim; Sacerdote, Carlotta; Aune, Dagfinn; Johansson, Mattias; Smith-Warner, Stephanie A; Zheng, Wei; Shu, Xiao-Ou (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-14)
      Background: Little is known about the association between physical activity before cancer diagnosis and survival among lung cancer patients. In this pooled analysis of 11 prospective cohorts, we investigated associations of prediagnosis leisuretime physical activity (LTPA) with all-cause and lung cancer–specific mortality among incident lung cancer patients. <p><p>Methods: Using self-reported data ...

    • Prediagnostic calcium intake and lung cancer survival: A pooled analysis of 12 cohort studies 

      Yu, Danxia; Takata, Yumie; Smith-Warner, Stephanie A.; Blot, William; Sawada, Norie; White, Emily; Freedman, Neal; Robien, Kim; Giovannucci, Edward; Zhang, Xuehong; Park, Yikyung; Gao, Yu-Tang; Chlebowski, Rowan T.; Langhammer, Arnulf; Yang, Gong; Severi, Gianluca; Manjer, Jonas; Khaw, Kay-Tee; Weiderpass, Elisabete; Liao, Linda M.; Caporaso, Neil; Krokstad, Steinar; Hveem, Kristian; Sinha, Rashmi; Ziegler, Regina; Tsugane, Shoichiro; Xiang, Yong-Bing; Johansson, Mattias; Zheng, Wei; Shu, Xiao-Ou (Journal article; Manuskript; Tidsskriftartikkel; Peer reviewed; Preprint, 2017-03-06)
      <p><i>Background</i>: Lung cancer is the leading cause of cancer death. Little is known about whether prediagnostic nutritional factors may affect survival. We examined the associations of prediagnostic calcium intake from foods and/or supplements with lung cancer survival.</p> <p><i>Methods</i>: The present analysis included 23,882 incident, primary lung cancer patients from 12 prospective cohort ...

    • Sex differences in risk of smoking-related lung cancer: results from a cohort of 600,000 Norwegians 

      Hansen, Merethe Selnes; Licaj, Idlir; Braaten, Tonje; Langhammer, Arnulf; Marchand, Loic Le; Gram, Inger Torhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-26)
      Whether women are more susceptible than men to smoking-related lung cancer has been a topic of controversy. To address this question, we compared risks of lung cancer associated with smoking by sex. Altogether, 585,583 participants from 3 Norwegian cohorts (Norwegian Counties Study, 40 Years Study, and Cohort of Norway (CONOR) Study) were followed until December 31, 2013, through linkage of data to ...

    • Smoking related lung cancer mortality by education and sex in Norway 

      Hansen, Merethe Selnes; Licaj, Idlir; Braaten, Tonje; Langhammer, Arnulf; Marchand, Loic Le; Gram, Inger Torhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-21)
      Lung cancer is one of the most common forms of cancer and the leading cause of cancer death worldwide, with tobacco smoking as the main cause [1]. In Norway, as in other western countries, smoking was more prevalent among men and in the highest social classes six to seven decades ago [2]. The proportion of male smokers increased until the 1960s, when it was around 65%. Among women, the peak (35%) ...

    • Validation of self-reported and hospital-diagnosed atrial fibrillation: The HUNT study 

      Malmo, Vegard; Langhammer, Arnulf; Bønaa, Kaare; Loennechen, Jan Pål; Ellekjær, Hanne (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-11)
      Background: Self-reported atrial fibrillation (AF) and diagnoses from hospital registers are often used to identify persons with AF. The objective of this study was to validate self-reported AF and hospital discharge diagnoses of AF among participants in a population-based study. Materials and methods: Among 50,805 persons who participated in the third survey of the HUNT Study (HUNT3), 16,247 ...